Does your bladder impairs your quality of life?

Do you suffer from urgency that is difficult to suppress?

Do you often feel the need to go to the toilet – even several times a night?

Do you have severe persistent pain in your lower abdomen?

If the answer to one or more questions is yes, you may have chronic inflammation of the bladder, or chronic cystitis.

Chronic bladder inflammation causes three main symptoms:

How does chronic cystitis develop?


A healthy bladder has a fine mucous protective layer that stops irritant substances in the urine from reaching the bladder wall. In chronic forms of cystitis this protective lining, known as the glycosaminoglycan layer (or GAG-layer), becomes damaged, so it fails to protect the bladder wall. Once this barrier is damaged, irritants from urine can reach the underlying structures and aggravate the neurons. This causes the symptoms we discussed above.

How can Gepan help?

Gepan is a pH neutral, sterile solution containing chondroitin sulphate (0.2%), a natural component of the GAG layer.

  • Susannah
    When the clinics were cancelled during the pandemic I felt I had no one to turn to for help. I knew that I didn't want to suffer the pain of having no treatment but the support I got from you when you sent me my Gepan was such a relief.
  • Angela
    I was nervous about using a catheter and self-instilling my Gepan as I have arthritis in my hands, but after speaking with you really helped. Taking the time to talk me through how to insert my catheter and connecting my Gepan was such a massive help.
  • Catherine
    You have been a life saver. Thank you for not just sending my Gepan to me when I couldn't get to the hospital but also for arranging for my catheters to be delivered straight to my door. You have been amazing and I don't know what I would have done without you.
  • Georgia
    I cannot thank you enough for helping me with my Gepan. Just having someone to talk to at the end of the phone and taking the time to listen to how I felt was fabulous.

Mode of action

Gepan attaches to the damaged areas of the bladder wall, just like a liquid bandage adheres onto a wound. As a result, the protective layer is restored, preventing the penetration of irritants into the deeper tissue. This way the bladder is protected from irritants in the urine and cystitis symptoms are reduced.

Gepan is proven through both clinical data and empirical evidence

Gepan’s effectiveness, safety and tolerability are confirmed by 286 patients with chronic cystitis.*

This study showed that all of the main symptoms of cystitis (pain, urgency and frequency) were significantly reduced after 3 months of treatment. In addition to that, both doctors (84%) and patients (82%) were highly satisfied by the treatment.