"Gepan is my go-to treatment of choice for patients with BPS/IC".

- Mr Haq, Clinical Director of Urology at Lancashire Teaching Hospitals
Mr HaqMr Haq

Relief from pain

Your abdominal pain should be relieved.

Relief from urge & frequency

You should need to pee less by day.

Better night's sleep

You should no longer need to get up to pee through the night.

Ease of use

Gepan is the easiest GAG therapy to self-instill.

Structure of a bladder

The GAG-layer is a mucous membrane inside the bladder that protects the bladder wall from irritants normally found in urine.

Gepan contains chondroitin sulphate, a natural component of the GAG-layer. Chondroitin sulphate temporarily rebuilds the essential protective layer of the bladder. By renewing the GAG layer, symptoms are relieved and as a result, your quality of life is improved.


Types of cystitis

Gepan is licensed for treatment of all types of chronic cystitis, including:

bladder pain syndrome/interstitial cystitis
recurrent UTIs
overactive bladder
chemotherapy and radiation induced cystitis

Slide Review "Every area of my life is better" Mia Eldekvist has been suffering from repeated urinary tract infections since she was 15. She spent her teenage years feeling constantly unwell and being hindered in her school and social life. Countless rounds of antibiotics were causing many side effects, such as thrush and digestion problems, and it took 4 years of therapy and diagnostic exams for her to be diagnosed with interstitial cystitis.

Then she discovered Gepan instill and life improved greatly. Mia learned how to self-catheterise and now uses Gepan any time she anticipates a flare up of symptoms:

"I use it every few weeks, but I do it more or less often depending on any flare-ups — it’s become my security blanket. Every area of my life is better with this treatment, and I feel much more in control now".
January 2018 Mia Eldekvist Gepan is easy to use, safe and effective. Order by email here.

Slide Preferred GAG-layer treatment (independent review). Easy, no-fuss instillation. No extra containers & no sharp disposals. Universal syringe tip quickly connects to most catheters. Non-viscous fluid is easily injected into the catheter. Made in Germany with highest standards of quality and care.

Free Yourself

Gepan is the easiest GAG instillation to use at home. Most people can learn to use a catheter themselves which then allows you to use Gepan in the comfort of your own home, at a time that is convenient for you.

No more travelling to clinics to have instillations, or sitting in waiting rooms. You can even get your prescriptions from your local pharmacy.

Talk to your doctor about Gepan or, if you have already been taught to self-catheterise, you can order directly here. We have resources for extra support, including guides on self-catheterising, and the video on the left.






You may also be interested in the Feel Free Chronic Pelvic/Bladder Pain Programme.

The 60-day course gets fantastic results in overcoming the pain, other symptoms and the wider physical, psychological and emotional effects of living with these chronic conditions.

There’s superb support in live Zoom meetings with the trainers, a community of people on a similar journey, as well as 1:1 calls and online contact.

Carla says: “This programme made such a big difference. I’m able to visit my family and friends more. Life is just better. I feel more alert, more alive! I feel good, and I wasn’t like this before.”

How to use Gepan

Slide 1 Wash your hands, then follow the manufacturer’s instructions to prepare the catheter. Slide 2 Unwrap Gepan syringe. Gepan’s innovative tip can be connected directly to most catheters; however, if you are having trouble connecting your preferred catheter, please do let us know and we will send you an adapter, as shown in the video. Slide 3 Pass urine as you would normally do, then wash around the urethral opening with water. Wash your hands again. Slide 4 Insert the catheter into the urethra and up into the bladder. For more detailed instructions, please download our male or female instillation guide. Slide 5 Finally, connect the other end of the catheter to Gepan syringe. Push the plunger slowly to instill the fluid into the bladder. Once all the liquid has been instilled, gently remove the catheter. Slide 6 Keep the liquid in your bladder for at least 30 minutes (longer the better).

FAQ about cystitis and Gepan

1Why are bladder pain syndrome/interstitial cystitis and overactive bladder so difficult to diagnose?
Bladder pain syndrome (BPS)/interstitial cystitis and Overactive bladder (OAB) are diagnosed by exclusion. In other words, several other possibilities, such as urological, gynecological, and internal disorders need to be excluded first, before a diagnosis can be made. This can often take a long time. In order to make a diagnosis, the specialist conducts a partially external examination (for e.g. cystoscopy, urodynamic studies, biopsy).
2Can diet affect my bladder symptoms?
A balanced diet generally contributes to better overall health. A sufficient intake of vitamins can prevent infections, for example. Patients should give preference to lighter and healthier foods, having smaller portions, more often.
3Can Gepan be used in combination with other medications?
Yes, Gepan can be used in combination with oral drugs. Interactions with medications such as antispasmodics, analgesics and antibiotics are unknown.  Gepan is not a systemic drug, it acts only locally, directly in the bladder wall. Therefore there is no reason to believe there would be any interactions with systemic medications.
4How do I keep Gepan?
Gepan ready-to-use disposable syringes can be stored at room temperature, but not above 25°C. Do not freeze Gepan. Keep only unopened syringes and discard unused leftovers immediately.
5Will Gepan cost me anything?
Gepan is available from your urologist/gynaecologist/nursing team or bought directly from Purple Orchid Health. Gepan is usually prescribed and is fully reimbursed in England, Scotland and Northern Ireland.
  • Georgia
    I cannot thank you enough for helping me with my Gepan. Just having someone to talk to at the end of the phone and taking the time to listen to how I felt was fabulous.
  • Catherine
    You have been a life saver. Thank you for not just sending my Gepan to me when I couldn't get to the hospital but also for arranging for my catheters to be delivered straight to my door. You have been amazing and I don't know what I would have done without you.
  • Angela
    I was nervous about using a catheter and self-instilling my Gepan as I have arthritis in my hands, but after speaking with you really helped. Taking the time to talk me through how to insert my catheter and connecting my Gepan was such a massive help.
  • Susannah
    When the clinics were cancelled during the pandemic I felt I had no one to turn to for help. I knew that I didn't want to suffer the pain of having no treatment but the support I got from you when you sent me my Gepan was such a relief.