Here you can find answers to frequently asked questions about cystitis and bladder complaints. Should you have any more questions about treatment with Gepan® instill, we will be happy to answer them individually.

Feel free to contact us.

What are chronic forms of cystitis?

Chronic forms of cystitis are frequently recurring diseases of the bladder, which are characterised by the following symptoms: frequent urination, strong and hard to suppress urgency and constant pain in the pelvic area. There are various forms of these diseases, such as interstitial cystitis (IC), overactive bladder (OAB), radiation cystitis and chronic recurrent urinary tract infections.

What causes chronic forms of bladder infection?

Chronic forms of cystitis are often associated with GAG-layer deficiency. The exact cause of interstitial cystitis and overactive bladder is unknown. In case of radiation cystitis, however, the condition is caused by radiation therapy in the pelvic area. Chronic, recurrent urinary tract infections often affect individuals with an underlying susceptibility to infections.

More about GAG-layer replenishing and Gepan® instill

Why are interstitial cystitis and overactive bladder so difficult to diagnose?

Interstitial cystitis (IC) and overactive bladder (OAB) are diagnosed by exclusion. In other words, several other possibilities, such as urological, gynecological, and internal disorders need to be excluded first, before a diagnosis can be made. This can often take a long time.

In order to make a diagnosis, the specialist conducts a partially external examination (for e.g. cystoscopy, urodynamic studies, biopsy).

Can diet affect the course of the disease?

A balanced diet generally contributes to better overall health. A sufficient intake of vitamins can prevent infections, for example. Patients should give preference to lighter and healthier foods, having smaller portions, more often. We have special diet tips available for patients with interstitial cystitis.

Read our practical tips to to improve daily life when suffering from chronic forms of cystitis.

Does pregnancy affect IC?

A few doctors have reported improved symptoms of interstitial cystitis in pregnant women. Experts believe that changes in progesterone levels may be responsible.

Are chronic forms of badder infection contagious?

No, interstitial cystitis, overactive bladder, and radiation cystitis are not infectious. Also the predisposition to chronic recurrent UTIs poses no risk of infection.

Can bladder transplants be done?

Bladder transplants are not done, since the bladder is not a vital organ. Namely, a bladder’s function is collecting urine. As a result of this function not being fulfilled, one’s quality of life significantly declines, but it is not a life-threatening situation. Therefore it is not justified to take the risks associated with organ transplantations.

These risks may include danger of rejection, followed by a lifelong intake of highly active drugs with many side effects. However, through special surgical methods, it is possible to create an acceptable replacement for the bladder.

Can Gepan® instill be used in combination with other medications?

Yes, Gepan® instill can be used in combination with oral drugs. Interactions with medications such as antispasmodics, analgesics and antibiotics are unknown and cannot be expected, since Gepan® instill is not a systemic drug, it acts only locally directly in the bladder wall.

How do I keep Gepan®instill?

Gepan® instill ready-to-use disposable syringes can be stored at room temperature, but not above 25°C. Do not freeze Gepan® instill. Keep only unopened syringes and discard unused leftovers immediately.

Who carries the costs of treatment?

Gepan® instill is available from your urologist/gynaecologist or bought directly from Purple Orchid Pharma webshop. Gepan® instill is available on prescription and is fully reimbursed in England, Scotland and Northern Ireland.